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POMC neurons express anorexigenic (appetite-suppressing) neuropeptides including POMC and cocaine- and amphetamine-regulated transcript (CART) [86, 87]

Despite the growing understanding of these mechanisms, translating this knowledge into effective therapies remains a significant challenge in the battle against this devastating disease

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In this study, we investigated the role of citrate in cell cycle progression and revealed PFKM as a citrate sensor

However, treatment with the proteasome inhibitor MG132 or the protease inhibitor E64d did not increase the accumulation of OsVIRK1 C4A -FLAG-HA in 35S:: OsVIRK1 C4A -FLAG-HA transgenic rice plants (Supplementary Fig