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WO2006050794A1 - Use of acetyl l-carnitine in combination with propionyl l-carnitine and sildenafil for the treatment of erectile dysfunction - Google Patents Use of acetyl l-carnitine in combination with propionyl l-carnitine and sildenafil for the treatment of erectile dysfunction Download PDF Info Publication number WO2006050794A1 WO2006050794A1 PCT/EP2005/011238 EP2005011238W WO2006050794A1 WO 2006050794 A1 WO2006050794 A1 WO 2006050794A1 EP 2005011238 W EP2005011238 W EP 2005011238W WO 2006050794 A1 WO2006050794 A1 WO 2006050794A1 Authority WO WIPO (PCT) Prior art keywords carnitine acid treatment erectile dysfunction acetyl Prior art date Legal status (The legal status is an assumption and is not a legal conclusion

L-carnitine is a nutrient prerequisite for energy generation in vital organs, including the liver, kidneys and brain (29,30)

Another placebo-controlled, double-blind, randomized study in 44 men with idiopathic asthenozoospermia found an increase in sperm motility in those given ALCAR alone (3 g/day) or ALCAR (1 g/day) plus L-carnitine (2 g/day) compared to those given L-carnitine alone (2 g/day) or a placebo (113)

When combined with an increased concentration of carnitine in urine, the suspicion of SPCD can often be confirmed by either molecular testing or functional studies assessing the uptake of carnitine in cultured fibroblasts

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