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When exogenous growth hormone enters the system, it binds the hGH receptor, activates JAK2/STAT5 signalling, drives IGF-1 production in the liver, stimulates longitudinal bone growth, and simultaneously activates lipolysis through a parallel pathway
Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo

4B), and a KEGG pathway analysis of hub targets is shown in Fig

doi: 10.2174/0929867323666160405111152
doi: 10.1373/49.2.327
