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For compounded products, specifically, the FDA has stated that some may have additional secret ingredients or other formulations

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Medication given this way is absorbed more slowly than if injected into a vein or taken by mouth (orally), sometimes over a period of 24 hours

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As a result of the tests, it was observed that 62% (18 of 29 patients) of the examined people developed an immediate reaction (including anaphylactic reactions: 1 after oral administration

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