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CBS deficiency resulted in reduced xCT and FTH levels, enhancing the propensity of cells to undergo ferroptosis (Fig
Moreover, since TETs function is to demethylate CpG islands of genomic DNA, this could be responsible for, or at least increase, global DNA hypomethylation, which could lead to chromosomal instability
10.1016/j.freeradbiomed.2015.12.002 Free Radic
Final ratings for each study reflected unanimous agreement
