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There, the pleiotropic beneficial effect, along with cytoprotection concept implementation, regulation of the increasing angiogenesis, increased VEGF, increased egr-1 gene, increased NO, or eNOS stimulation, and counteraction of the increased free radical formation, occur through a network of closely interconnected pathways presented in this review (see Section 1, Section 2 and Section 3)

The control group received saline instead of the peptide

Specifically, the animals showed improved behavior in the elevated body swing test, forelimb retraction, beam walking and bilateral forepaw grip strength, all common measures of neurological function

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Transfection was carried out using Lipofectamine 3000 Kit on cells at 50% confluence for 6 hours, followed by protein extraction 48 hours post-transfection