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Of note, GLS1 inhibition causes an elevation of the ROS level and induces GPT2 expression via ATF4, which again implies the importance of ATF4-mediated metabolic adaption during glutamine starvation
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Gen Hosp Psychiatry 74:2231
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An elevated lactulose/mannitol ratio indicates pathological tight junction widening the hallmark of leaky gut and guides the intensity of gut lining repair protocols required alongside Candida treatment
