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These findings demonstrate decreased MT3 expression alongside copper as a common feature of ALS and MS supporting previously reported evidence for copper dysregulation in these diseases

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Concurrently, these advancements will strengthen the theoretical foundation for the management of AKI and CKD, ultimately facilitating the standardization of berberine-based therapeutic strategies for various renal disorders

By presenting a comprehensive approach to CBD receptor activation across various pathologies, this review offers a more integrated understanding of how CBD can influence a wide range of therapeutic outcomes, making it a valuable addition to the growing body of CBD literature for both researchers and clinicians
