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Location: San Diego Melanie Fay Pearlman Sickness-conditioned learning in day-old chicks: memory formation depends on time of lithium chloride injection
Specifically, tubacin inhibits the activity and expression of HDAC6, inhibits P62 and LC3-II, and upregulates the expression of beclin-1 (the key regulators of autophagy) by enhancing the acetylation of -tubulin at lysine 40 residues, thereby restoring autophagy levels and motility in AGE-treated podocytes (Liang et al., 2020)
A: The primary mechanistic difference is receptor selectivity
