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[68] [45] Ligands [edit] Agonists [edit] Mixed [edit] Antagonists [edit] Steroidal antiandrogens (e.g., cyproterone acetate, chlormadinone acetate, spironolactone, oxendolone) Nonsteroidal antiandrogens (e.g., flutamide, nilutamide, bicalutamide, enzalutamide, apalutamide, RU-58841) N-Terminal domain antiandrogens (e.g., bisphenol A, EPI-001, ralaniten, JN compounds) [70] As a drug target [edit] The AR is an important therapeutic target in prostate cancer

Those exceptional Qualifying variants most likely to be disease related were categorized as Key Qualifying variants, and additionally met at least one of the following categories: Pathogenic or Likely Pathogenic (P/LP) variants: These variants are listed in ClinVar 6 as being either pathogenic (P) or likely pathogenic (LP) for disease