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Description
Free radicals and peroxides are produced in large quantities in T2DM via glucose oxidation and non-enzymatic protein glycation, which can overwhelm antioxidant defense mechanisms leading to cellular damage (119), a phenomenon termed hyperglycemic or metabolic memory (128)
Pathology 2014;46:375-82
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doi: 10.1093/ajcn/81.1.277S
Excessive OS can have deleterious effects on the cellular milieu and can result in impaired cellular growth in the embryo or apoptosis resulting in embryo fragmentation
