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After the release of TSH into the blood, it binds to its receptor (TSH-R) on the basolateral aspect of the thyroid follicular cell

To further characterize compound engagement of TGR in ex vivo worms using an orthogonal assay, inhibition of TGR activity in newly transformed schistosomula (NTS, skin-stage worms) was assessed using a TrxR-selective fluorescent probe 43,44 , TRFS-Green

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Experiments using opioid and dopamine antagonist drug challenges suggest that specific changes in dopaminergic pathways lead to the development of RLS

Antioxidants 11(2):295
