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A., Jotte R
Upon injection of the low number of cells, control mice develop local and distant tumours after about 8 weeks
The authors instead propose that a pathway involving unreacted DHA is most likely, due to the maximum attainable browning varying directly with DHA concentration
This process releases the inflammatory factor IL-1, leading to neuroinflammation, which can be reversed by inhibitors related to inflammatory signaling pathways [71]
[PubMed 9397220] 2078
