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Moreover, the presence of HSP60 on the cell surface and in the extracellular milieu has been linked with the activation of immune responses, where it acts as a damage-associated molecular pattern (DAMP) and signals to immune cells, thereby influencing inflammatory pathways, 134,135 which is particularly relevant in understanding autoimmune diseases and cancer

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Authors contributions All authors were involved in the planning and hypothesizing of this review article

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