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We recently reported that genetic loss of Sigmar1 suppressed mitochondrial respiration and led to large, hyperfused mitochondria in mouse hearts 32
Preclinical Combination Data (ALCAR + Alpha-Lipoic Acid) Preclinical studies in aged rats have demonstrated that combining ALCAR with alpha-lipoic acid (ALA) synergistically improves cognitive function more effectively than either compound alone

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Chuck RS, Williams JM, Goldberg MA, Lubniewski AJ

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