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(1) Classical GPx (GPx1) is reported to be expressed in red blood cells and liver, lung, and kidney tissues and is located in the cytosol, nucleus, and mitochondria

Notably, the majority of valerolactone in urine existed in conjugated forms, suggesting that microbial-derived metabolites, once absorbed, undergo host phase II modification before renal clearance

There is a desperate and urgent need for inexpensive and non-toxic therapeutic agents that can pause the exacerbation of alcohol-induced hepatic steatosis

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