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Description
2.5.3 Extrapolation of animal data to man The use of animals has been essential to help define the molecular basis and the progression of model nephropathies, but it may be inappropriate to extrapolate animal toxicology data directly to man because of marked species, strain, dietary, and sex differences

B12 shots are usually safe

Kennedy G, Norris G, Spence V, McLaren M, Belch JJ

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To calculate the U.S
