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Fertil Steril 2004;81:1578-84

A large dog can burn through it fast

Cochrane Handbook for Systematic Reviews of Interventions , Version 6.0 (Updated July 2019)

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Also contact a doctor if you have any of these symptoms: blood in the urine very dark, red, or orange urine frequent foamy urine, especially with leg swelling other unusual color, odor, or consistency changes
