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[DOI] [PubMed] [Google Scholar] [93].Mayr L, Grabherr F, Schwarzler J, et al

The IDH3 isoform is involved in the TCA cycle where it oxidatively decarboxylates isocitrate to 2-oxoglutarate (-ketoglutarate)

(2021) E3 ubiquitin ligase Casitas B lineage lymphoma-b and its potential therapeutic implications for immunotherapy
The abundance of GSH in tumor cells as an endogenous antioxidant has been demonstrated to capture ROS and dilute the anti-tumor effect

When the tumours reached a volume of approximately 50 mm 3 , mice were randomized into two treatment groups: vehicle and palbociclib (100 mg kg 1 five times per week)