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[4] ESSENCE is the strongest human evidence that a GLP-1 agonist can improve both steatohepatitis and fibrosis, and it is the single most important data point for the CagriSema liver hypothesis because semaglutide is half of the combination

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Lipid dysregulation promotes the pathogenesis of PD by oxidative stress and inflammation, such as proinflammatory lipid mediators of platelet-activating factors, which play a key role in the progressive neurodegeneration associated with -synuclein intracellular traffic in PD

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