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However, recent evidence shows that, like CD38, CD157 is upregulated in ageing tissues 45 and may have a role in ageing-related diseases, such as rheumatoid arthritis and cancer 46

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Souza EBD, Whitehouse PJ, Price DL, Vale WW (1987) Abnormalities in corticotropin-releasing hormone (CRH) in Alzheimers disease and other human disorders

The biological activity attributed to BPC-157 in preclinical literature derives from the peptide sequence itself not the counterion