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The correct posture is enthusiasm about the science paired with sobriety about the still-open Phase 3 and safety questions

It decreases LPS-induced increases in the levels of reactive oxygen species (ROS), IL-6, and TNF-alpha in RAW 264.7 cells when used at a concentration of 10 M

Convenient for patients who prefer not to inject and are primarily seeking gut-healing benefits

A high salt concentration in the medium promotes fibrillation and lowers down the critical concentration of the protein to undergo LLPS by neutralizing the charges at the N and C termini and promoting aggregation of the NAC region (Sawner et al., 2021)

However, unlike the hits obtained from the P3 1 21 XChem screen, the hits from the P4 1 2 1 2 XChem screen spanned a larger surface area of the TIN2 TBM binding site (Fig