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These results suggest that NRF2 serves as a biomarker for predicting ferroptosis by targeting LDHB and SLC7A11 in KRAS -dependent cancer cells, consistent with previous finding that LDHB plays a unique role in KRAS-mutant lung cancer [27, 56]

To further explore the association of ASXL1 and BRD4 in the cellular context, we performed chromatin immunoprecipitation coupled with deep sequencing (ChIP-seq) of endogenous ASXL1, BRD4 and BAP1 and assessed genomic occupancies of these proteins in human HEK293T cells

Since LAM can act on the mTOR pathway, the inhibitory effect of baicalein on this pathway can also hinder the function of LAM (198)

Table 2 Energy intake, protein intake, body weight, and plasma free amino acid levels in Experiment 1