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Finally, to provide further proof that HuR controls KGA levels, we used the CRISPR-Cas9 knock-in system to modify the GLS gene by introducing a fluorescence protein (mKO2 49 ) within exon 19 to express KGA fused to mKO2 at its C-terminus (Fig

Redox Biol (2017) 11:6139

Note that the mice fed ketones did not lose weight they just gained less than others

Interestingly, these lipid-storage particles, while found in the intestinal cells, are the dominant lipid-rich particles found in the epidermal cells

Certain clinical conditions common in hemodialysis patients such as malaise, muscle weakness, cardiomyopathy and cardiac arrhythmias may be related to abnormal carnitine metabolism