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Absorption problems Even with adequate intake, absorption can be reduced by: Certain gastrointestinal conditions affecting the stomach or small intestine Some medications Age-related reduction in stomach acid (which can affect absorption) Autoimmune gastritis (often historically referred to as pernicious anaemia) This is a well-recognised cause of B12 deficiency and may require ongoing management

Dissecting DCs composed of heterogeneous populations into functional subpopulations defined by molecular markers should enhance our understanding of DC biology and improve the clinical outcomes of DC vaccines (88)

41,43 This may be the reason that, unlike the p53 DBD/p28 complex (Figure 1D), p28 does not bind to the L1 loop of the p63 DBD

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Bardelkov et al