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doi: 10.2174/0929867043365387
In the ovarian radiation injury model, the upregulation of the Toll-Like Receptor 4 (TLR4)- NF-B-TNF- axis can create a self-reinforcing inflammatory microenvironment, thus exacerbating tissue dysfunction
These agents work by binding to bile acids in the intestine, preventing their reabsorption and promoting their excretion, thus reducing circulating bile acid levels and alleviating symptoms of cholestasis
He said that as patients continue to take oral medication over time, the medication becomes less effective
Methods 247 , 175186 (2001)
