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165 It is important to acknowledge that, while these mouse models are widely regarded as representative of CAC, they still exist significant differences from human IBD and CAC

It can enhance the activity of NRF2 in HepG2 human liver cancer cells

Arch Toxicol 71:131141 Kishida K, Saida N, Yamamura N, Iwai Y, Sasabe T (2001) Cysteine conjugate of methazolamide is metabolized by -lyase

CUR decreases AFB 1 -induced apoptosis-related gene expression AFB 1 can induce acute stress responses in animals, resulting in apoptosis and a series of stress responses in the kidney, ultimately resulting in kidney injury

the Natural Science Foundation of Guangdong Province, China (2016A0303 13229, 2017A030313784, 2018A030310286)