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5-amino-1MQ, an analogue from our initial series of NNMT inhibitors with low IC 50 value (IC 50 = ~1 M;[17]), and high cell membrane permeability (Table 2), produced the greatest reduction of intracellular 1-MNA levels at a concentration of 10 M among tested inhibitors (Figure 2D)

Because AOD-9604 does not raise IGF-1 and is not a growth hormone analog in the traditional sense, cycling requirements are less strict than with CJC-1295/Ipamorelin but a provider should guide any protocol based on labs and a patient's overall goals

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doi: 10.1056/NEJMoa0810780

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