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doi: 10.1038/ncb3071
LCAT deficiency in humans results in decreased HDL cholesterol and Apo A-I levels and a higher percentage of small HDL particles (72)
Plus, research shows it may have a positive effect on preventing heart disease, which is associated with ED
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We introduced the unc1(vlt10) mutation, and as expected, unc1(vlt10) increased neuronal aggregate formation in the ventral nerve cord of young adults, further demonstrating the requirement of unc1 in protein homeostasis (Fig 1E and F)
