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Most of the subjects included in this study were patients whose seizures could not be fully controlled despite using effective doses of 1st generation and 2nd generation antiepileptic drugs 31

While compensatory angiogenesis serves as an adaptive mechanism to counteract tissue hypoxia in the aging brain, pathological angiogenesis can exacerbate neurodegenerative processes by promoting BBB dysfunction, inflammation, and vascular instability

Long-distance translocation of metals from roots to shoots has been proposed to occur amongst others via the xylem in a PC-dependent manner
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