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doi: 10.3389/fmed.2023.1183344

Tobin DJ and Paus R

Cytokine storm in individuals with severe COVID-19 decreases endothelial cell antioxidant defense via downregulation of the Nrf2 transcriptional factor

HLA-DR reference range is under 25 %, however, we established a cut off level of 35 % to high level of expression, which was not achieved by all patients

The poor permeability of anti-TB drugs within granulomas, coupled with ineffective regulation of extracellular signaling, allows M.tb to adapt and develop drug resistance
