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Description
Larkin, P
One arm of the antibody binds to HLA-G on the tumor cell, while the other arm binds to CD3 on the T cell
AAG-catalyzed excision of the damaged DNA base give rise to apurinic (AP) sites, which are then converted to DNA single-strand breaks (SSBs) through an incision step, mediated by AP endonuclease 1 (Demple and Sung 2005)
Nrf2 also activates the genes encoding the four major NADPH producing enzymes, G6PD, PGD, ME1, and IDH1, for reducing oxidized glutathione and other cellular components
doi: 10.1016/0090-4295(90)80215-9 65 NadorEMausserEMaratheJGPolitchJAThurmanARWhaleyKJet al
