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For example, a radiological investigation comparing adolescents with high genetic risk for bipolar disorder and schizophrenia with matched controls, found evidence of significant reduction in coupling in both frontalstriatal and frontalparietal networks, as well as lower recruitment of DLPFC during a sustained attention task ( Neuroimaging in Patients with Bipolar Disorder Neuroimaging studies of bipolar disorder are frequently characterized by equivocal findings and, in some instances, a failure to replicate previous results

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Enhancing metformin effects by adding gut microbiota modulators to ameliorate the metabolic status of obese, insulin-resistant hosts