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Folate deficiency increases oxidative and nitrosative stress, activating NF-B, while homocysteine triggers NF-B activation and IL-6/IL-1 production in vascular and myeloid cells, biochemical routes through which impaired remethylation amplifies inflammation

By sequestering excess free iron, FTH helps maintain iron homeostasis and prevents the accumulation of labile iron, which is critical for initiating the lipid peroxidation process in ferroptosis 68

After 9 days of reproduction, the reproduction multiplier for nematodes treated with sterile water reached 687-fold, while those treated with ds GFP , ds BxGST3 , and ds BxGST1 showed reproduction multipliers of 643-, 124-, and 156-fold, respectively ( Figure 7C )

J Pathol 247(5):697707 Xia X, Lei L, Wang S, Hu J, Zhang G (2020) Necroptosis and its role in infectious diseases

2.1.2 Execution The searches for studies were conducted in the PubMed, Science Direct, and Springer pre-selected databases, which contain peer-reviewed journals aligned with the research theme