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Description
This approach avoids the common pitfalls of small-molecule drugs that affect multiple targets in the body

In this vicious cycle sometimes depression results in anxiety too

Hence, by targeting the enzymatic activity of SARM1, inhibitors may effectively prevent the depletion of NAD + , thereby maintaining cellular energy homeostasis and enhancing neuronal resilience, potentially expanding the treatment landscape for various neurological conditions

Patients should be particularly vigilant about monitoring for gastrointestinal side effects, such as nausea or diarrhea, and report any persistent symptoms to their healthcare provider
Ethnopharmacology 137 (3), 12911299
