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Description
Subsequently, the carboxyl groups are activated through the combined action of carbodiimide and N-hydroxysuccinimide to form stable amide bonds

Adv Neurol 68: 720

Luberda Z

Moreover, quercetin inhibits aluminum-induced cyt-c translocation, downregulates Bax and p53, upregulates Bcl-2 and caspase-3 activation, and decreases DNA fragmentation [70]
Notably, the hippocampus, a region crucial for memory and learning, is particularly sensitive to these inflammatory insults, potentially linking systemic inflammation and BBB disruption to long-term cognitive deficits (Peng et al., 2019
