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The report indicates that simultaneous inhibition of the GSH and TXN pathways is a well-established route to trigger cell death 46

Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD

The majority of the information is obtained on animals, including rats, mice, rabbits, and dogs

Hernandez JL, Woodrow KA (2022) Medical applications of porous biomaterials: features of porosity and tissue-specific implications for biocompatibility

172 In contrast, mitophagy serves as a preventative strategy against inflammation via eliminating damaged mitochondria and avoiding the production of excess ROS, hence the change in mitophagy will result in the alternation of inflammasome activation