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Description
The liver serves as the primary source of plasma GSH, thereby playing a crucial role in maintaining interorgan GSH homeostasis
However, the role of active transport mediated by multiple transporters become prominent to platinum-uptake
Their pH-responsive behavior is predictable, and release rates are relatively stable, reducing non-specific release
The cranial cavity is always complete, in contrast to hydrocephalus, and usually of normal conformation, although occasionally there is mild doming of the skull or thickening of the cranial bones
It achieves this by activating caspase-3 and caspase-9, as well as modulating apoptosis-related genes such as Bax and Bcl-2 (Ghafouri-Fard et al., 2021b)
