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The day after, neurospheres were washed twice with PBS 1X and further incubated for 1 h with Dy-Light -conjugated secondary antibodies (1:500, all from Abcam), and DAPI (1 g/mL, ThermoFisher) in blocking solution (3.5% BSA in PBS 1X) under constant gyratory shaking

Overview: BPC 157 (Body Protection Compound 157) is a synthetic peptide widely recognized for its regenerative and healing properties

In contrast, methylcobalamin is attached to a methyl group , which is a naturally occurring compound in the body and is easily utilized by the body

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SAM is also involved in the regulation of tau phosphorylation.51 Moreover, hyperhomocysteinaemia has been shown to be associated with a significant increase in amyloid level and amyloid deposition on cortex and hippocampus in mouse models of AD.53 Overall, vitamin B 12 deficiency may have implications in the neuropathological process of AD