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Drachler JC, Poland F, et al
Other signaling pathways, such as AMPK, AKT, and Wnt/catenin, have been implicated in regulating glutamine metabolism and offer potential avenues for therapeutic intervention
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Additionally, the presence of hydroxyl groups at the 3- and 5-positions enhances antioxidant activity
Furthermore, irisin activated the SIRT1 signaling pathway, leading to the deacetylation of HIF-1 and PGC-1, which suppressed apoptosis and enhanced cell viability in MPP + -treated SH-SY5Y cells
