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These mice can be identified by performing DNA sequencing in their OhNo genes and then bred with each other

ROS/Ca 2+ signaling mediated by damaged mitochondria through MAMs may further affect chromatin homeostasis and gene transcription [266, 339]
The supernatant was injected onto a 5-ml HisTrap HP column (Cytiva), and (H3/His-H4) 2 or (His-CENP-A/H4) 2 was eluted with buffer containing 20 mM Tris, pH 7.5, 2 M NaCl, 5% glycerol, 5 mM BME, and 300 mM imidazole
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