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In the mitochondria, LC also scavenges ROS through its antioxidant property

In addition, these PAAD authors call for well conducted unbiased RCTs with well defined dosing and criteria, or reviews of the literature that either embrace all the available literature or precisely describe why the results of some manuscripts were disregarded, plus better scrutiny of submitted manuscripts by peer reviewers for journals

doi: 10.1007/978-1-4419-8216-2_7 [DOI] [PubMed] [Google Scholar] 498

It has decades of randomized controlled trial data behind it and is widely regarded as the reference-standard topical retinoid against which newer molecules are measured

doi: 10.1039/D2FO01358D 137 TomeD