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97 Hyperuricemia, by inducing oxidative stress and inflammation, diminishes the expression of eNOS and the synthesis of NO, while elevating levels of inflammatory cytokines such as IL-6 and TNF- , ultimately impairing endothelial function

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10.1016/j.bcp.2020.114365 53 NoblancA.PeltierM.Damon-SoubeyrandC.KerchkoveN.ChaboryE.VernetP.et al (2012)

These researchers commented that the increases in cortical and total BMC were due to an increased growth of the bones with increased bone dimensions