what is a melanotic macule Mystery behind labial and oral macules: Clinical, dermoscopic and pathological aspects of Laugier-Hunziker syndrome Melanotic macule detected in the
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This is a drug that prevents binding of natural molecules like B-endorphins to opioid receptors, effectively blocking activation of the receptors leading to increased GnRH secretion and a resultant increase in LH

Knowing these causes can help find the real reason for lip color changes
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