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Western blot analysis confirmed strong expression and undetectable expression of MCT1 (molar mass 54 kDa, apparent molar mass 40 kDa) in BT20 and MDA-MB-231 cells, respectively, while MCT4 was detected in MDA-MB-231 but not BT20 (Fig

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6.3 ALA Alpha-lipoic acid (ALA) is a disulfide compound with unique biochemical properties: it is both water- and fat-soluble, enabling it to act throughout the cell, and it can counteract excessive ROS induced by chronic hypoxia by neutralizing free radicals, chelating metal ions, and regenerating other antioxidant substances (such as vitamins C and E and glutathione)