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Smoking is a potential risk factor for regular use of high-dose vitamin B12 supplements as hepatic tumorigenesis may be promoted

Lian J, Kuang W, Jia H, Lu Y, Zhang X, Ye C, Gu J, Lv Y, Yu J, Zhang Y, Lu X, Zhao Y, Yang D, Wang K, Zhao P, Yu Y, Bai L, Zhang J

doi: 10.1074/jbc.M007136200 126 HoffmannI.EugeneE.NassifX.CouraudP.-O.BourdoulousS

Promotion of neuronal survival and regeneration By activating the Brain-derived neurotrophic factor/tropomyosin receptor kinase B (BDNF-TrkB) signaling pathway, Rg1 can protect neurons against degeneration while controlling synaptic plasticity ( The therapeutic results for PD treatment improve when neuronal survival and regeneration receive support through optimized energy metabolism and enhanced autophagic processes