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Based on our own investigations, as well as from those already performed by other teams, both in human and in experiments done in animal models, mostly in rats (wistar) and mice (balb c) , we can draw the conclusions regarding the dose ranging and the time necessary to observe an effect of glisodine as follows: 1) From animal and human data, it can be deduced that the physiological effect of glisodine on the prevention of exogenous induced oxidative stress depends on both length of administration and dosing

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10.1016/j.psep.2024.01.100 144 ProkischJ.NguyenD

The combination of cisplatin and RSL3 also caused a significant reduction in mean tumour size when compared with all other groups (Fig