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Meanwhile, following closely behind CagriSema is Novos zenagamtide, a unimolecular peptide agonist of the GLP-1 and amylin receptors, which has been linked to 24% weight loss in obesity and more than 14% weight loss in diabetes in phase 2

Moreover, the significant bioenergetic and metabolic requirements of dopaminergic neurons make them especially vulnerable to mitochondrial stress

The evidence base is preclinical: findings come from animal and in-vitro models, and BPC-157 is not approved for human or veterinary use

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