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77 In contrast, endothelial dysfunctionan early and independent predictor of cardiovascular eventscontributes to both macrovascular and microvascular pathology, playing a central role in the progression of diabetic CVD 78,79 (Fig

However, if your constipation doesnt improve with dietary changes such as drinking more water and increasing your fiber intake, or if you have a family history of colon cancer, consult your doctor

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This was accompanied by a significant reduction in released cytosolic proteins such as myoglobin and creatine kinase, malondialdehyde (MDA), as well as a decrease in markers for purine metabolism such as hypoxanthine and xanthine oxidase [54,61]

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