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Modifying a drug delivery system with a brain targeting agent is one of the effective approaches to develop a brain targeting drug delivery system

Nephron Physiol (2014) 128(1-2):17

Lysine-arginine imbalance overcomes therapeutic tolerance governed by the transcription factor E3-lysosome axis in glioblastoma

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Clinical evidence indicates that GH replacement therapy improves the lipid profile (reducing LDL-C and increasing HDL-C), restores vascular endothelial function, and lowers inflammatory markerssuch as high-sensitivity C-reactive protein, IL-6, and TNF-in patients with growth hormone deficiency, while also reducing carotid intima-media thickness (175)